Tag Archives: PTSD

Stress relief could someday be an immunization away

A researcher examines a sample of Mycobacterium vaccae. Source: www.colorado.edu

There’s a bacterium found on the shores of a Ugandan lake that could help reduce our stress. Scientists recently injected it into stressed-out mice with promising results.

The bacterium, called Mycobacterium vaccae, reduces inflammation in the brain, which in turn prepares the brain to respond better to stress. These findings could lead to better treatments for PTSD, anxiety, and depression.

In the study, researchers injected mice with the bacterium three times, a week apart. Eight days after the last injection, the mice’s brains showed higher levels of an anti-inflammatory protein in the hippocampus, a region of the brain involved in regulating anxiety.

They then placed the mice in a cage with a larger, aggressive mouse. The injected mice showed fewer symptoms of anxiety in the stressful situation, and they had lower levels of a stress-induced, inflammation promoting protein called HMGB1 and higher levels of an anti-inflammatory receptor called CD200R1.

Researchers say other probiotics (helpful bacteria) could have similar effects, and studies are under way to explore how they can be used. One potential use would be as a preventative treatment for people going into stressful situations, like combat or emergency room employment.

There’s so much more to understand about how mental illness works, and this is an interesting step in the right direction.

Satu Woodland is owner and clinician of Mental Health Solutions, an integrative mental health practice located at Bown Crossing in Boise, Idaho. If you would like to discuss the information in this blog further with her, please call 208-918-0958. She sees adolescents and adults. Information in this blog is not intended as medical advice. Please consult your health care provider about decisions regarding your health.

 

Is there a relationship between trauma and obsessive compulsive disorder?

Very interesting study came out this month in the European Journal of Psychotraumatology. It studied patients who were diagnosed both with obsessive-compulsive disorder (OCD) and posttraumatic stress disorder. (PTSD) For these people, repetitive behavior patterns, rituals and compulsions may ward off anxiety and may serve as a coping mechanism to control reminders of traumatic events. So, if a person was raped at a young age, that person may have obsessions related to being dirty or unclean and may cope with those obsessions by washing his hands several times a day. Some patients suffer so severely that she may wash her hands raw enough to make them bleed. These patients are truly in a lot of distress.
This study was a case report of a 49 years old Dutch man who was raped as a child by an unknown man. The patient was treated with Paxil (an antidepressant) as well as with 9 sessions of psychotherapy, particularly eye movement desensitization and reprocenssing (EMDR), and an exposure type of therapy. It was observed that the PTSD symptoms went away before the OCD symptoms did.
This studies conclusion found that there is a connection between PTSD and OCD and by treating the PTSD first, one may be able to subsequently cure the OCD as well.
It is my belief that for many people, EMDR can be a faster route to get relief in those who have experienced trauma and also suffer from OCD symptoms.

EMDR reduces the subjective vividness and objective memory accessibility.

We’ve heard a lot about EMDR or Eye Movement Desensitization and Reprocessing. There have been much research supporting its efficacy, many books written, even U-tube videos made demonstrating its usefulness. What does it do exactly? The mechanism isn’t completely clear.
In eye movement desensitization and reprocessing (EMDR), a treatment for post-traumatic stress disorder (PTSD), patients make eye movements (EM) during trauma recall. A recent study in Cogn Emot. 2012 Jul 6 showed that EMDR apparently reduces the subjective vividness of the memories, making the memories easier to deal with and handle. Thereby making the memory fade faster in susequent visits.